The hospital is on the Jinja–Tororo highway, in the town of Bugiri, about 73 kilometres (45 mi), east of Jinja Regional Referral Hospital. Bugiri General Hospital is a 100-bed, government-owned hospital. It serves Bugiri District and parts of the districts of Iganga, Busia, Namayingo Mayuge, and Namutumba.
The hospital was built in 1967 by the Obote I government. Over the years, the hospital infrastructure has deteriorated, the equipment has become antiquated and the hospital has become under-staffed.